Monday, February 17, 2014

#1 of 5 short stories on the Origin of Life - The cellular/acellular divide


5 short stories on the Origin of Life

What is life, anyways? We can label the items around us as living or dead fairly easily: Me? Alive. Chair? No. Plant that I haven’t watered in a month? Might still be kickin’ -- gotta love succulents. Computer? I wish. Than I could be chatting up Scarlett Johansson like that guy in Her. Below are five short (but true!) stories on the origins of life here on our cozy little planet earth.  

The Honey Mushroom stretches
 for miles underground
1) The cellular/acellular divide

But really the division for life and non-life is hard to pinpoint because it lies at the cellular/acellular divide. From big Blue whales, Giant Sequoia trees, and the truly massive Honey mushroom in Oregon down to the smallest Paramecium, or the truly tiny Mycoplasma genitalium (one of the smallest bacteria) all of these diverse organisms get labeled as living because they are all forms of self-replicating, ribosome-utilizing cellular life.

Viruses, Protein, DNA all fall short of this definition of life. The largest known virus, the Pandoravirus, at 500 nm wide and 1000 nm long is bigger than the tiny archaeon Nanoarchaeum equitans  (300 x 300 nm) and even though both depend on host cells for survival, the poor Pandoravirus doesn’t get the label of being alive. M. genitalium at least has the potential to grow and divide outside of a host cell as it has the ribosomes necessary to translate RNA to protein. 
Nanoarchaeum equitans, the smallest cellular life 
Viruses, even the largest viruses, can not make their own protein and for that reason don’t meet the requirements for life. But the Pandoravirus is still a recent discovery, and the cellular/acellular divide may be blurred further. If a Pandoravrius stole a few genes for ribosomes could it cross the divide and come to life?

The next story on Magma oceans and marauding asteroids soon to come... but this is my first attempt at a blog, so excuse my ignorance as I try to figure it all out.